Marshall College scientist wins new NIH grant for coronary heart assault analysis
Sandrine Pierre, Ph.D., Affiliate Scientific Director on the Marshall Institute for Interdisciplinary Analysis (MIIR), obtained a brand new grant from the Nationwide Institutes of Well being (NIH) to additional her analysis on Myocardial infarction, referred to as coronary heart assault.
Pierre was awarded an NIH (R15) prize of $ 440,000 price of analysis, over three years, designed to help small-scale analysis tasks strengthening the standard of the analysis. analysis surroundings of the establishment. With this grant, Pierre and his group will discover a brand new Na / Ok-ATPase / Src pathway as a goal in ischemia / reperfusion harm to restrict coronary heart dysfunction within the hope of creating new therapeutic interventions. for the therapy of myocardial infarction and coronary heart failure.
Myocardial infarction stays the main reason behind dying in industrialized nations, making practically one in three deaths in america and leading to important incapacity amongst survivors. The examine will take a look at two separate interventions within the acute section of myocardial infarction in addition to within the persistent section of the opposing cardiac transforming, section that in the end results in coronary heart failure within the growing variety of coronary heart assaults. people surviving a coronary heart assault.
This examine will construct on Pierre's earlier analysis that recognized the cardioprotective properties of the Na / Ok-ATPase signaling pathway in cardiac myocytes.
Marshall College College of Drugs Joan C. Edwards